SCHEMBL7148444

SCHEMBL7148444

O=S1(=O)C=Cc2ccc(Cl)cc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 8/20 0.53
CA2 P00918 6/20 0.53
CA1 P00915 5/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.53
STAT3 P40763 1/20 0.53
MTOR P42345 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
HIF1A Q16665 1/20 0.53
PTGDR2 Q9Y5Y4 1/20 0.47
PLCG2 P16885 1/20 0.43
CHEK1 O14757 1/20 0.39
DAPK3 O43293 1/20 0.39
MAP4K4 O95819 1/20 0.39
RET P07949 1/20 0.39
PIM1 P11309 1/20 0.39
LTK P29376 1/20 0.39
GRK5 P34947 1/20 0.39
CSNK1A1 P48729 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11638186 0.83 CA9 (0.53) CA9CA2CA1MEN1NPC1
SCHEMBL31028807 0.75 CA2 (0.53) CA9CA2CA1MEN1NPC1
SCHEMBL10371873 0.75 CA2 (0.53) CA9CA2CA1MEN1NPC1
SCHEMBL922607 0.75 CA9 (0.58) CA9CA2CA1MEN1NPC1
SCHEMBL7610058 0.75 CA2 (0.53) CA9CA2CA1MEN1NPC1
SCHEMBL1371709 0.75 CA2 (0.53) CA9CA2CA1MEN1NPC1
SCHEMBL13261334 0.75 CA2 (0.53) CA9CA2CA1MEN1NPC1
SCHEMBL7130486 0.75 CA2 (0.53) CA9CA2CA1MEN1NPC1
SCHEMBL23991757 0.71 CA9 (0.49) CA9CA2CA1MEN1NPC1
SCHEMBL3842267 0.71 CA2 (0.54) CA9CA2CA1MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527977-B2 Solvent dispersion EASTMAN KODAK COMPANY 2003-03-04 US disclosed
US-20020009656-A1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY 2002-01-24 US disclosed
US-6245255-B1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY 2001-06-12 US disclosed
US-6214499-B1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY 2001-04-10 US disclosed
US-6093510-A A METHINE DYE DISPERSED IN A SOLVENT EASTMAN KODAK COMPANY (US) 2000-07-25 US disclosed
CN-1248728-A Liquid crystal light-filtering dye used for imaging element EASTMAN KODAK CO (US) 2000-03-29 CN disclosed
EP-0985970-A1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY (US) 2000-03-15 EP disclosed
EP-0985969-A1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY (US) 2000-03-15 EP disclosed