SCHEMBL7148469

SCHEMBL7148469

O=C(O)c1cc(C2CCC(O)CC2)ccc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 3/20 0.76
ESR2 Q92731 2/20 0.50
PTGS2 P35354 2/20 0.49
MEN1 O00255 2/20 0.49
KDR P35968 2/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
TNF P01375 1/20 0.49
CYP3A4 P08684 1/20 0.49
HSPD1 P10809 1/20 0.49
THRB P10828 1/20 0.49
CYP2C9 P11712 1/20 0.49
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
CASP1 P29466 1/20 0.49
CYP2C19 P33261 1/20 0.49
BRCA1 P38398 1/20 0.49
RECQL P46063 1/20 0.49
CASP7 P55210 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27881571 0.93 ACMSD (0.86) ACMSDPTGS2MEN1KDRKMT2A
SCHEMBL6535512 0.85 ACMSD (0.73) ACMSDESR2PTGS2MEN1KDR
SCHEMBL27965931 0.85 ACMSD (1.00) ACMSDPTGS2MEN1KDRKMT2A
SCHEMBL2533359 0.85 ACMSD (1.00) ACMSDPTGS2MEN1KDRKMT2A
SCHEMBL11773568 0.83 ACMSD (0.65) ACMSDPTGS2MEN1KDRKMT2A
SCHEMBL1315430 0.82 ACMSD (0.73) ACMSDPTGS2MEN1KDRKMT2A
SCHEMBL7147427 0.82 ACMSD (0.73) ACMSDESR2PTGS2MEN1KDR
SCHEMBL11777656 0.81 ACMSD (0.72) ACMSDESR2PTGS2MEN1KDR
SCHEMBL28822507 0.79 ACMSD (0.64) ACMSDESR2MEN1KMT2AKDM4E
SCHEMBL30394377 0.78 PDE4B (0.49) ACMSDESR2KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1295863-A1 Liquid crystalline \"laterally polymerizable\" compounds Rolic AG (CH) 2003-03-26 EP disclosed