Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | CD81 | P60033 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL7650274 | 1.00 | TP53 (0.36) | TP53GRIK2GRIK1CD81CYP2C9 | |
| SCHEMBL5716965 | 0.88 | — | — | |
| SCHEMBL17817 | 0.88 | — | — | |
| SCHEMBL17819 | 0.88 | — | — | |
| Methylethylamine SCHEMBL7641428 | 0.86 | GRIK1 (0.34) | GRIK2GRIK1CD81CYP2C9PTGS1 | |
| Dimethylamine SCHEMBL1224400 | 0.86 | GRIK1 (0.36) | GRIK2GRIK1CD81CYP2C9PTGS1 | |
| Dimethylamine SCHEMBL525464 | 0.86 | GRIK1 (0.36) | GRIK2GRIK1CD81CYP2C9PTGS1 | |
| Bicarbonate SCHEMBL10996733 | 0.85 | GRIK2 (0.39) | GRIK2GRIK1CD81CYP2C9PTGS1 | |
| Water SCHEMBL11376129 | 0.85 | — | — | |
| SCHEMBL1401918 | 0.85 | GRIK2 (0.39) | GRIK2GRIK1CD81CYP2C9PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118460122-A | Waterproof PVAc white latex and preparation method thereof | 沈阳爱克浩博化工有限公司 | 2024-08-09 | — | — | CN | claimed |
| US-5401783-A | Adhesion-promoting agents incorporating polyvalent cations | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1995-03-28 | — | — | US | claimed |
| EP-0276934-A2 | Explosive composition | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1988-08-03 | — | — | EP | claimed |
| US-3985698-A | Method for improving emulsion paint by adding an acrylic resin produced from a tertiary amine containing ethylenically unsaturated monomer | KANSAI PAINT COMPANY, LTD. (JA) | 1976-10-12 | — | — | US | claimed |
| CN-118460122-A | Waterproof PVAc white latex and preparation method thereof | 沈阳爱克浩博化工有限公司 | 2024-08-09 | — | — | CN | disclosed |
| EP-4321145-A1 | DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT | Shofu Inc. (JP) | 2024-02-14 | — | — | EP | disclosed |
| CN-112105659-B | Statistical copolymer latex, use thereof, and method for producing statistical copolymer latex | 电化株式会社 | 2023-05-12 | — | — | CN | disclosed |
| CN-115135329-A | Method for culturing cells derived from epithelial tissue and composition comprising cells cultured by the culturing method | JBM株式会社 | 2022-09-30 | — | — | CN | disclosed |
| CN-115068346-A | Dental photocurable composition having excellent handling properties and storage stability | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| CN-115068348-A | Curable composition for dental use having excellent storage stability | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| CN-115068345-A | Dental adhesive composition having excellent storage stability | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| CN-115068347-A | Photocurable composition having excellent depth of cure | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| EP-0337422-B1 | Waterdilutable binders and their use as coatings especially in the car industry | HERBERTS & CO GMBH (DE) | 1995-11-15 | — | — | EP | disclosed |
| US-5395659-A | Cationic polymers, clear coats, automobiles | HERBERTS GMBH (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0404033-B1 | Aqueous binder solution or dispersion for cathodically depositable aqueous coatings and its use in cathodic electrodeposition | HERBERTS & CO GMBH (DE) | 1994-12-21 | — | — | EP | disclosed |
| US-4909915-A | Water dilutable poly (meth)acrylate containing ionic groups | HERBERTS GESELLSCHAFT MIT BESCHRANKTER (DE) | 1990-03-20 | — | — | US | disclosed |
| US-4865705-A | Non-auto crosslinking binder combination, aqueous coating compound containing the same and its use | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-12 | — | — | US | disclosed |
| US-4865704-A | HYDROXYL GROUP, AMINO GROUP CONTINING EPOXIDE RESIN, AND AMINO GROUP POLYMER BLEND | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-12 | — | — | US | disclosed |
| CN-88100209-A | EXPLOSIVE COMPOSITION | — | 1988-08-10 | — | — | CN | disclosed |
| EP-0276934-A2 | Explosive composition | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1988-08-03 | — | — | EP | disclosed |