SCHEMBL1401918

SCHEMBL1401918

CCC=C(C)C(=O)O.CCC=C(C)C(=O)O.CCC=C(C)C(=O)O.CCC=C(C)C(=O)O.[SiH4]

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIK2 Q13002 2/20 0.39
GRIK1 P39086 1/20 0.39
PTGS1 P23219 1/20 0.34
AKR1C3 P42330 1/20 0.34
CD81 P60033 1/20 0.34
FFAR3 O14843 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
EP300 Q09472 1/20 0.33
TRPA1 O75762 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
CYP2C9 P11712 1/20 0.31
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17817 0.97
SCHEMBL5716965 0.97
SCHEMBL17819 0.97
Oxalic Acid SCHEMBL7522641 0.94 GRIK2 (0.39) GRIK2GRIK1PTGS1AKR1C3CD81
Water SCHEMBL11376129 0.94
Ammonia Solution, Strong SCHEMBL534130 0.94
Bromide SCHEMBL9604104 0.94
Oxalic Acid SCHEMBL7522649 0.94 GRIK2 (0.39) GRIK2GRIK1PTGS1AKR1C3CD81
Hydrochloric Acid SCHEMBL2564983 0.94
Bicarbonate SCHEMBL10996733 0.94 GRIK2 (0.39) GRIK2GRIK1PTGS1AKR1C3CD81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2018-12-06 US disclosed
EP-2292672-B1 Biocompatible polymers and co-polymers comprising amino acids in the side chain CIS PHARMA AG (CH) 2018-05-09 EP disclosed
US-9839719-B2 Biocompatible polymers and co-polymers, and uses thereof CIS PHARMA AG (CH) 2017-12-12 US disclosed
US-20170152335-A1 Biocompatible polymers and co-polymers, and uses thereof HITZ HANS (CH) 2017-06-01 US disclosed
EP-1888660-B1 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN CIS PHARMA AG (CH) 2017-05-17 EP disclosed
EP-2523982-B1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES CIS PHARMA AG (CH) 2015-04-29 EP disclosed
US-8980957-B2 Methods for the preparation of biocompatible polymers, the polymers and their uses CIS PHARMA AG (CH) 2015-03-17 US disclosed
US-20120329902-A1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES SCHAEFER ROLF (CH) 2012-12-27 US disclosed
EP-2523982-A1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES Chemisches Institut Schaefer AG (CH) 2012-11-21 EP disclosed
WO-2011085988-A1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES CHEMISCHES INSTITUT SCHAEFER AG (CH) 2011-07-21 WO disclosed
EP-2292672-A2 Biocompatible polymers and co-polymers comprising amino acids in the side chain Chemisches Institut Schaefer AG (CH) 2011-03-09 EP disclosed
US-20090232871-A1 Biocompatible polymers and co-polymers, and uses thereof HITZ HANS 2009-09-17 US disclosed
EP-1888660-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN Chemisches Institut Schaefer AG (CH) 2008-02-20 EP disclosed
WO-2006126095-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN CHEMISCHES INSTITUT SCHAEFER AG (CH) 2006-11-30 WO disclosed
US-4323467-A POLYOXYALKYLENE ETHYLENEDIAMINE NONIONIC SURFACTANT SYNTEX (U.S.A.) INC. (US) 1982-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090232871-A1 Biocompatible polymers and co-polymers, and uses thereof PPIH, ARG1, P4HA1 GRIK2 2002/4885GRIK1 2806/4885PTGS1 136/4885
US-20170152335-A1 Biocompatible polymers and co-polymers, and uses thereof ARG1, CRYAA, COL1A1 GRIK2 2589/4885GRIK1 2024/4885PTGS1 485/4885
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof ARG1, CRYAA, COL1A1 GRIK2 2589/4885GRIK1 2024/4885PTGS1 485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.