Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 10/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24069882 | 0.83 | CA1 (0.57) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL10652 | 0.83 | CA1 (0.57) | CA1CA2CA7CTSKCYP2D6 | |
| Ammonia Solution, Strong SCHEMBL9235390 | 0.81 | CA1 (0.55) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL305895 | 0.81 | CA1 (0.55) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL2550753 | 0.81 | CA1 (0.55) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL11201598 | 0.80 | CA1 (0.50) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL19489244 | 0.80 | CA1 (0.50) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL963465 | 0.80 | CTSK (0.53) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL7771571 | 0.80 | CA1 (0.50) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL2058674 | 0.80 | CTSK (0.53) | CA1CA2CA7CTSKCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525059-B1 | Mitogen-activated protein kinases (MAP); | G. D. SEARLE & COMPANY | 2003-02-25 | — | — | US | disclosed |