SCHEMBL7148771

SCHEMBL7148771

C=COCCOC(=O)c1cc(O)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.58
CA1 P00915 5/20 0.58
CA2 P00918 5/20 0.58
CA7 P43166 5/20 0.58
CA9 Q16790 5/20 0.58
CA14 Q9ULX7 5/20 0.58
SERPINE1 P05121 1/20 0.57
EGFR P00533 7/20 0.44
ALOX5 P09917 1/20 0.43
PTGS2 P35354 1/20 0.43
LMNA P02545 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13286843 0.87 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL20110399 0.85 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL7092473 0.83 CA12 (0.68) CA12CA1CA2CA7CA9
SCHEMBL15844998 0.80 TSHR (0.44) SERPINE1LMNATDP1KDM4E
SCHEMBL2966217 0.80 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL15425253 0.79 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL4593811 0.78 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL28275082 0.78 TYR (0.63) CA12CA1CA2CA7CA9
SCHEMBL27438505 0.78 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL8385248 0.78 ESR1 (0.59) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1295863-A1 Liquid crystalline \"laterally polymerizable\" compounds Rolic AG (CH) 2003-03-26 EP disclosed