SCHEMBL71489

SCHEMBL71489

COC(=O)C1CCC2OC1CCC2C(=O)OC

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 2/20 0.57
PTPN1 P18031 2/20 0.57
PPP1CC P36873 2/20 0.57
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM3 P20309 1/20 0.43
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KDM4E B2RXH2 1/20 0.39
GMNN O75496 1/20 0.39
LMNA P02545 1/20 0.39
PMP22 Q01453 1/20 0.39
TFPI2 P48307 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
THPO P40225 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8649646 0.92 PPM1B (0.59) PPM1BPTPN1PPP1CCCHRM2CHRM4
SCHEMBL21000602 0.86 PPM1B (0.50) PPM1BPTPN1PPP1CCCHRM2CHRM4
SCHEMBL9657738 0.86 PPM1B (0.50) PPM1BPTPN1PPP1CCCHRM2CHRM4
SCHEMBL26701653 0.84 SLC6A3 (0.50) PPM1BPTPN1PPP1CCSLC6A4SLC6A3
SCHEMBL22645863 0.84 SLC6A3 (0.50) PPM1BPTPN1PPP1CCSLC6A4SLC6A3
SCHEMBL13805963 0.84 SLC6A3 (0.50) PPM1BPTPN1PPP1CCSLC6A4SLC6A3
SCHEMBL5400994 0.84 SLC6A3 (0.50) PPM1BPTPN1PPP1CCSLC6A4SLC6A3
SCHEMBL10446578 0.84 SLC6A3 (0.50) PPM1BPTPN1PPP1CCSLC6A4SLC6A3
SCHEMBL21984119 0.83 SLC6A3 (0.49) PPM1BPTPN1PPP1CCSLC6A4SLC6A3
SCHEMBL11791640 0.83 PPM1B (0.48) PPM1BPTPN1PPP1CCCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PPM1B 3974/4885PTPN1 3997/4885PPP1CC 4613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.