Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152582 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL7642898 | 0.82 | — | — | |
| SCHEMBL6909872 | 0.79 | — | — | |
| SCHEMBL6903948 | 0.77 | CYP1A2 (0.32) | — | |
| SCHEMBL6906458 | 0.77 | CYP1A2 (0.32) | — | |
| SCHEMBL6909526 | 0.77 | CYP1A2 (0.32) | — | |
| SCHEMBL6692865 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL6908739 | 0.75 | MAPT (0.31) | — | |
| SCHEMBL6909504 | 0.74 | — | — | |
| SCHEMBL3716244 | 0.74 | ALDH1A1 (0.34) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H2060-H1 | Cyclobutyl silanes for catalysts useful for making highly isotactic olefin polymers | ENGELHARD CORPORATION | 2003-03-04 | — | — | US | claimed |
| US-H2060-H1 | Cyclobutyl silanes for catalysts useful for making highly isotactic olefin polymers | ENGELHARD CORPORATION | 2003-03-04 | — | — | US | disclosed |