Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.42 |
| ▸ | CA1 | P00915 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 6/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099870 | 1.00 | CA2 (0.42) | CA2CA1ALDH1A1TSHRCYP4F2 | |
| SCHEMBL9302678 | 1.00 | CA2 (0.42) | CA2CA1ALDH1A1TSHRCYP4F2 | |
| SCHEMBL7103948 | 1.00 | CA2 (0.42) | CA2CA1ALDH1A1TSHRCYP4F2 | |
| SCHEMBL3858379 | 0.97 | — | — | |
| SCHEMBL249264 | 0.88 | — | — | |
| SCHEMBL11147913 | 0.85 | CA2 (0.48) | CA2CA1CA9CA12CA3 | |
| SCHEMBL8069056 | 0.85 | CA2 (0.48) | CA2CA1CA9CA12CA3 | |
| SCHEMBL30041571 | 0.85 | CA2 (0.48) | CA2CA1CA9CA12CA3 | |
| SCHEMBL10798852 | 0.85 | CA2 (0.48) | CA2CA1CA9CA12CA3 | |
| SCHEMBL10457263 | 0.82 | CA2 (0.43) | CA2CA1TSHRCA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9956293-B2 | Targeted therapeutics | MADRIGAL PHARMACEUTICALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-9956293-B2 | Targeted therapeutics | MADRIGAL PHARMACEUTICALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-9597343-B2 | Targeted therapeutics | SYNTA PHARMACEUTICALS CORP. (US) | 2017-03-21 | — | — | US | disclosed |
| US-9597343-B2 | Targeted therapeutics | SYNTA PHARMACEUTICALS CORP. (US) | 2017-03-21 | — | — | US | disclosed |
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| EP-1020437-A1 | PROCESS FOR PRODUCING HALOGENOALKYLSULFONAMIDE DERIVATIVES | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5705494-A | INDUCED BY ADMINISTERING; COMBAT SIDE EFFECTS OF GLUCOCORTICOIDS | ROUSSEL-UCLAF (FR) | 1998-01-06 | — | — | US | disclosed |
| US-5679788-A | ANTIESTEROGENIC AGENT | ROUSSEL UCLAF (FR) | 1997-10-21 | — | — | US | disclosed |
| EP-0629635-B1 | New 19-nor 11-beta-phenoxysulfonamide or 11-beta-phenoxyalkylsulfonylurea steriod derivatives, a process and intermediates for their production and their use as medicaments and pharmaceuticals containing them | ROUSSEL UCLAF (FR) | 1997-03-19 | — | — | EP | disclosed |
| US-5556845-A | ANTIESTROGEN | ROUSSEL UCLAF (FR) | 1996-09-17 | — | — | US | disclosed |
| US-5494907-A | ANTIESTROGEN ACTIVITY | ROUSSEL UCLAF (FR) | 1996-02-27 | — | — | US | disclosed |
| EP-0381132-B1 | Imidazopyridazines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0629635-A1 | New 19-nor 11-beta-phenoxysulfonamide or 11-beta-phenoxyalkylsulfonylurea steriod derivatives, a process and intermediates for their production and their use as medicaments and pharmaceuticals containing them | ROUSSEL UCLAF (FR) | 1994-12-21 | — | — | EP | disclosed |
| US-5202324-A | Bronchodilators | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0381132-A1 | Imidazopyridazines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-08 | — | — | EP | disclosed |