Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271778 | 1.00 | MEN1 (0.58) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL5146172 | 1.00 | MEN1 (0.58) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL27168273 | 0.91 | PGR (0.54) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL19349131 | 0.86 | MEN1 (0.61) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL1370501 | 0.86 | MEN1 (0.56) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL1370500 | 0.86 | MEN1 (0.56) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL11164223 | 0.83 | KMT2A (0.57) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL1642206 | 0.83 | MEN1 (0.49) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL8472603 | 0.83 | MEN1 (0.49) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL40674 | 0.82 | KMT2A (0.57) | MEN1KMT2AALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728147-B1 | RECEPTOR SPECIFIC ATRIAL NATRIURETIC PEPTIDES | GENENTECH INC (US) | 2003-02-12 | — | — | EP | claimed |
| US-5846932-A | Receptor specific atrial natriuretic peptides | GENENTECH, INC. (US) | 1998-12-08 | — | — | US | claimed |
| US-5665704-A | VASODILATORS, HYPOTENSIVE AGENTS; METABOLIC STABILITY | GENENTECH, INC. (US) | 1997-09-09 | — | — | US | claimed |
| EP-0728147-A1 | RECEPTOR SPECIFIC ATRIAL NATRIURETIC PEPTIDES | GENENTECH, INC. (US) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013296-A1 | RECEPTOR SPECIFIC ATRIAL NATRIURETIC PEPTIDES | GENENTECH, INC. (US) | 1995-05-18 | — | — | WO | claimed |
| CN-115068347-A | Photocurable composition having excellent depth of cure | 株式会社松风 | 2022-09-20 | — | — | CN | disclosed |
| CN-106661084-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2021-08-31 | — | — | CN | disclosed |
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10351595-B2 | — | — | 2019-07-16 | — | — | US | disclosed |
| US-10351595-B2 | — | — | 2019-07-16 | — | — | US | disclosed |
| EP-0728147-B1 | RECEPTOR SPECIFIC ATRIAL NATRIURETIC PEPTIDES | GENENTECH INC (US) | 2003-02-12 | — | — | EP | disclosed |
| US-5990341-A | Diastereoselective synthesis hydroxyethylene dipeptide isosteres | EMORY UNIVERSITY (US) | 1999-11-23 | — | — | US | disclosed |
| US-5846932-A | Receptor specific atrial natriuretic peptides | GENENTECH, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| US-5665704-A | VASODILATORS, HYPOTENSIVE AGENTS; METABOLIC STABILITY | GENENTECH, INC. (US) | 1997-09-09 | — | — | US | disclosed |
| US-5587514-A | Diastereoselective synthesis of hydroxyethylene dipeptide isosteres | EMORY UNIVERSITY (US) | 1996-12-24 | — | — | US | disclosed |
| EP-0728147-A1 | RECEPTOR SPECIFIC ATRIAL NATRIURETIC PEPTIDES | GENENTECH, INC. (US) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995014655-A1 | DIASTEREOSELECTIVE SYNTHESIS OF HYDROXYETHYLENE DIPEPTIDE ISOSTERES | EMORY UNIVERSITY (US) | 1995-06-01 | — | — | WO | disclosed |
| WO-1995013296-A1 | RECEPTOR SPECIFIC ATRIAL NATRIURETIC PEPTIDES | GENENTECH, INC. (US) | 1995-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351595-B2 | — | MRPL21, PRSS1, PEPD | MEN1 3458/4885KMT2A 4084/4885LMNA 2198/4885 |
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | MRPL21, PEPD, CTSC | MEN1 2531/4885KMT2A 3283/4885LMNA 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.