Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15024815 | 0.83 | CHRM2 (0.35) | KCNH2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL23471056 | 0.82 | MCHR1 (0.32) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL13241378 | 0.80 | CHRM2 (0.37) | KCNH2MEN1KMT2AALDH1A1CHRM2 | |
| SCHEMBL1408760 | 0.77 | — | — | |
| SCHEMBL936173 | 0.77 | — | — | |
| SCHEMBL2760168 | 0.77 | KMT2A (0.41) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL12663243 | 0.75 | MEN1 (0.37) | KCNH2MEN1KMT2APOLB | |
| Iodide SCHEMBL28268785 | 0.74 | KMT2A (0.44) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL7152117 | 0.74 | CYP1A2 (0.41) | KCNH2ALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL7177278 | 0.74 | PIK3CD (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260454-A1 | CONDENSED PYRIMIDINE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2017-12-27 | — | — | EP | disclosed |
| EP-1334094-A1 | CHOLESTEROL LOWERING BENZO[B]THIOPHENES AND BENZO[D]ISOTHIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002036584-A1 | CHOLESTEROL LOWERING BENZO`B! THIOPHENES AND BENZO`D! ISOTHIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-05-10 | — | — | WO | disclosed |