SCHEMBL7149763

COc1ccc(CO[C@H]2[C@@H](O[C@@H]3O[C@@H](C)[C@@H](OCc4ccccc4)[C@@H](OCc4ccccc4)[C@@H]3OCc3ccccc3)[C@@H](CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)O[C@@H](Sc3ccc(C)cc3)[C@@H]2OC(=O)c2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	NT5E	P21589	1/20	0.37

▸	FGF2	P09038	1/20	0.36

▸	MDK	P21741	1/20	0.36

▸	PTPN1	P18031	9/20	0.33

▸	PTPN2	P17706	5/20	0.33

▸	HRAS	P01112	1/20	0.32

▸	PTPN11	Q06124	1/20	0.30

▸	CDC25B	P30305	3/20	0.30

▸	CDC25A	P30304	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7021624	0.91	NT5E (0.39)	NT5EFGF2MDKPTPN1PTPN2
SCHEMBL7030616	0.88	SSTR5 (0.33)	—
SCHEMBL7027238	0.88	FGF2 (0.38)	NT5EFGF2MDKPTPN1
SCHEMBL7026503	0.87	LGALS3 (0.38)	NT5EPTPN1
SCHEMBL7031768	0.86	FGF2 (0.41)	NT5EFGF2MDKPTPN1PTPN2
SCHEMBL7026185	0.82	NT5E (0.43)	NT5EFGF2MDKPTPN1PTPN2
SCHEMBL7026186	0.81	FGF2 (0.33)	NT5EFGF2MDKPTPN1PTPN2
SCHEMBL7028496	0.79	FGF2 (0.36)	FGF2MDK
SCHEMBL7026507	0.78	NT5E (0.38)	NT5EFGF2MDKPTPN1PTPN2
SCHEMBL13298919	0.78	NT5E (0.46)	NT5EFGF2MDKPTPN1PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6538117-B1	Linear sequence of three or more glycosyl units linked to one another by glycosidic linkages; database of reactivity values for glycosyl donors	THE SCRIPPS RESEARCH INSTITUTE	2003-03-25	—	—	US	disclosed