Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148188 | 0.91 | PTGS2 (0.51) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7148413 | 0.89 | PTGS2 (0.52) | PTGS2PTGS1P2RY6ALOX5 | |
| SCHEMBL7148172 | 0.89 | PTGS2 (0.52) | PTGS2PTGS1P2RY6ALOX5 | |
| SCHEMBL7151252 | 0.89 | PTGS2 (0.61) | PTGS2PTGS1P2RY6ALOX5 | |
| SCHEMBL7146315 | 0.88 | PTGS2 (0.66) | PTGS2PTGS1P2RY6DRD5DRD3 | |
| SCHEMBL7142459 | 0.88 | PTGS2 (0.66) | PTGS2PTGS1P2RY6DRD5DRD3 | |
| SCHEMBL7144214 | 0.86 | PTGS2 (0.54) | PTGS2PTGS1P2RY6DRD5DRD3 | |
| SCHEMBL7146282 | 0.85 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL7145968 | 0.84 | PTGS2 (0.52) | PTGS2PTGS1P2RY6DRD5DRD3 | |
| SCHEMBL6092246 | 0.84 | PTGS2 (0.75) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |