Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.55 |
| ▸ | CTSS | P25774 | 10/20 | 0.47 |
| ▸ | CTSL | P07711 | 7/20 | 0.47 |
| ▸ | CTSV | O60911 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450296 | 1.00 | CTSK (0.55) | CTSKCTSSCTSLCTSV | |
| SCHEMBL4456044 | 1.00 | CTSK (0.55) | CTSKCTSSCTSLCTSV | |
| SCHEMBL13677295 | 1.00 | CTSK (0.55) | CTSKCTSSCTSLCTSV | |
| SCHEMBL13677196 | 0.95 | CTSK (0.60) | CTSKCTSSCTSLCTSV | |
| SCHEMBL4451529 | 0.95 | CTSK (0.60) | CTSKCTSSCTSLCTSV | |
| SCHEMBL4446420 | 0.95 | CTSK (0.60) | CTSKCTSSCTSLCTSV | |
| SCHEMBL4457746 | 0.89 | CTSK (0.64) | CTSKCTSSCTSLCTSV | |
| SCHEMBL4459390 | 0.89 | CTSK (0.64) | CTSKCTSSCTSLCTSV | |
| SCHEMBL13677305 | 0.89 | CTSK (0.64) | CTSKCTSSCTSLCTSV | |
| SCHEMBL7152746 | 0.89 | CTSK (0.64) | CTSKCTSSCTSLCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769940-B1 | INDENE sPLA2 INHIBITORS | LILLY CO ELI (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-1996003120-A1 | INDENE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |