Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935541 | 0.98 | MAPT (0.68) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL14661687 | 0.98 | MAPT (0.68) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL178398 | 0.94 | MAPT (0.74) | MAPTPRSS1HTTGAAALDH1A1 | |
| SCHEMBL3297792 | 0.85 | MAPT (0.73) | MAPTSYKHTTGAAALDH1A1 | |
| SCHEMBL11518048 | 0.84 | MAPT (0.80) | MAPTPRSS1HTTGAAALDH1A1 | |
| SCHEMBL2065837 | 0.84 | MAPT (1.00) | MAPTHTTGAAALDH1A1 | |
| SCHEMBL854573 | 0.83 | MAPT (0.46) | MAPTPRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL28699276 | 0.83 | MAPT (0.70) | MAPTSYKHTTGAAALDH1A1 | |
| SCHEMBL13639541 | 0.83 | MAPT (0.70) | MAPTPRSS1HTTGAAALDH1A1 | |
| SCHEMBL11748511 | 0.82 | MAPT (0.52) | MAPTPRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1350102-A2 | DETECTION OF ANALYTES | Sensors for Medicine and Science, Inc. (US) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002054067-A2 | DETECTION OF ANALYTES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2002-07-11 | — | — | WO | disclosed |