Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33646 | 0.89 | MAPT (0.50) | MAPTPRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11696545 | 0.87 | PRSS1 (0.50) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL7149998 | 0.83 | MAPT (0.71) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL11748511 | 0.82 | MAPT (0.52) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL14661687 | 0.82 | MAPT (0.68) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL11935541 | 0.82 | MAPT (0.68) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL28861449 | 0.81 | ABL1 (0.50) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL457665 | 0.81 | APP (0.50) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL9011408 | 0.79 | ABL1 (0.53) | MAPTPRSS1F2PRSS2PRSS3 | |
| SCHEMBL28385928 | 0.79 | APP (0.49) | MAPTPRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473025-B1 | Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer | OREAL (FR) | 2012-03-28 | — | — | EP | claimed |
| EP-0969796-B1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | OREAL (FR) | 2003-10-22 | — | — | EP | claimed |
| US-20030172472-A1 | Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain | L'OREAL S.A. (FR) | 2003-09-18 | — | — | US | claimed |
| US-20020184716-A9 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL S.A. (FR) | 2002-12-12 | — | — | US | claimed |
| CN-1248577-A | Novel cation type 4-oxyindole, its oxidation dyeing, dyeing composition and dyeing method for keration fibre | OREAL (FR) | 2000-03-29 | — | — | CN | claimed |
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | claimed |
| CN-1051727-A | Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| CN-118103023-A | Retarder composition and dye set comprising same | 莱雅公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118043027-A | Process for dyeing and/or lightening keratin fibres | 莱雅公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-112312883-B | Device for dispensing hair coloring products using dye compositions and oxidizing compositions comprising scleroglucan gum | 莱雅公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117715615-A | Composition comprising at least one oxidation dye, 1, 3-propanediol, at least one alkaline agent and at least one fatty substance | 莱雅公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117715610-A | Composition for simultaneously bleaching and dyeing keratin fibers and method for using same | 莱雅公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117651546-A | Oxidation retardant composition | 莱雅公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-1090181-C | N-substituted 4-hydroxyindole derivatives and keratin fibre dyeing compsns. containing same | OREAL (FR) | 2002-09-04 | — | — | CN | disclosed |
| US-6383230-B1 | COLORFASTNESS, PHOTOSTABILITY, WATERPROOFING, WEATHERPROOFING | L'OREAL (FR) | 2002-05-07 | — | — | US | disclosed |
| CN-1344255-A | Novel cationic oxidation bases, their use for dyeing keratin fibres, dyeing compsns. and dyeing methods | OREAL (FR) | 2002-04-10 | — | — | CN | disclosed |
| CN-1248577-A | Novel cation type 4-oxyindole, its oxidation dyeing, dyeing composition and dyeing method for keration fibre | OREAL (FR) | 2000-03-29 | — | — | CN | disclosed |
| CN-1189820-A | N-substituted 4-hydroxyindole derivatives and keratin fibre dyeing compsns. containing same | OREAL (FR) | 1998-08-05 | — | — | CN | disclosed |
| US-5567421-A | COLORFAST, WASHFAST, WEATHERPROOF, AND PERSPIRATION RESISTANT HAIR DYE | L'OREAL (FR) | 1996-10-22 | — | — | US | disclosed |
| CN-1051727-A | Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030172472-A1 | Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain | KRT18, MB, MDN1 | MAPT 1430/4885PRSS1 3345/4885F2 1497/4885 |
| US-20020184716-A9 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | KRT18, COX6C, MT-CO1 | MAPT 1767/4885PRSS1 2982/4885F2 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.