Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.84 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150006 | 1.00 | ITGB3 (0.84) | ITGB3ITGA2BCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7141576 | 0.91 | ITGB3 (1.00) | ITGB3ITGA2BCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7141583 | 0.91 | ITGB3 (1.00) | ITGB3ITGA2BCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7010229 | 0.86 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7008545 | 0.86 | ITGB3 (0.90) | ITGB3ITGA2BITGAV | |
| SCHEMBL7152283 | 0.80 | ITGB3 (1.00) | ITGB3ITGA2BCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7152293 | 0.80 | ITGB3 (1.00) | ITGB3ITGA2BCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6792014 | 0.79 | ITGB3 (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL29557195 | 0.76 | ITGB3 (0.58) | ITGB3ITGA2BITGAV | |
| SCHEMBL7010002 | 0.76 | ITGB3 (0.90) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224186-B1 | PYRIDYL-CONTAINING SPIROCYCLIC COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION | MILLENNIUM PHARM INC (US) | 2003-09-24 | — | — | EP | disclosed |
| EP-1224186-A2 | PYRIDYL-CONTAINING SPIROCYCLIC COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION | COR THERAPEUTICS, INC. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030780-A2 | PYRIDYL-CONTAINING SPIROCYCLIC COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION | COR THERAPEUTICS, INC. (US) | 2001-05-03 | — | — | WO | disclosed |