Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869912 | 1.00 | ADORA2A (0.67) | ADORA2AADORA1NPC1RAB9AMEN1 | |
| SCHEMBL7150238 | 1.00 | ADORA2A (0.67) | ADORA2AADORA1NPC1RAB9AMEN1 | |
| SCHEMBL6863273 | 0.86 | ADORA2A (0.71) | ADORA2AMEN1KMT2A | |
| SCHEMBL6863643 | 0.84 | ADORA2A (0.73) | ADORA2AMEN1KMT2A | |
| SCHEMBL7150287 | 0.83 | ADORA2A (0.65) | ADORA2AADORA1NPC1RAB9AMEN1 | |
| SCHEMBL6867465 | 0.83 | ADORA2A (0.65) | ADORA2AADORA1NPC1RAB9AMEN1 | |
| SCHEMBL7150291 | 0.83 | ADORA2A (0.65) | ADORA2AADORA1NPC1RAB9AMEN1 | |
| SCHEMBL6873056 | 0.82 | ADORA2A (0.65) | ADORA2A | |
| SCHEMBL6871917 | 0.80 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL6868028 | 0.80 | ADORA2A (1.00) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506772-B1 | Pharmaceutically active salts thereof with activity as adenosine receptor ligands are disclosed. These compounds are the adenosine receptor. | HOFFMANN-LA ROCHE INC. | 2003-01-14 | — | — | US | claimed |
| US-6506772-B1 | Pharmaceutically active salts thereof with activity as adenosine receptor ligands are disclosed. These compounds are the adenosine receptor. | HOFFMANN-LA ROCHE INC. | 2003-01-14 | — | — | US | disclosed |