Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150291 | 1.00 | ADORA2A (0.65) | ADORA2AADORA1PLATHTR7NPC1 | |
| SCHEMBL6867465 | 1.00 | ADORA2A (0.65) | ADORA2AADORA1PLATHTR7NPC1 | |
| SCHEMBL6867753 | 0.86 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL6872004 | 0.83 | ADORA2A (0.47) | ADORA2ACNR2 | |
| SCHEMBL6867359 | 0.83 | ADORA2A (0.62) | ADORA2A | |
| SCHEMBL6869912 | 0.83 | ADORA2A (0.67) | ADORA2AADORA1NPC1RAB9AMEN1 | |
| SCHEMBL7150238 | 0.83 | ADORA2A (0.67) | ADORA2AADORA1NPC1RAB9AMEN1 | |
| SCHEMBL7150247 | 0.83 | ADORA2A (0.67) | ADORA2AADORA1NPC1RAB9AMEN1 | |
| SCHEMBL6867784 | 0.82 | ADORA2A (0.47) | ADORA2AADORA1 | |
| SCHEMBL6871917 | 0.79 | ADORA2A (1.00) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506772-B1 | Pharmaceutically active salts thereof with activity as adenosine receptor ligands are disclosed. These compounds are the adenosine receptor. | HOFFMANN-LA ROCHE INC. | 2003-01-14 | — | — | US | disclosed |