Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.92 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.92 |
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL624311 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL64728 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL28046864 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL64729 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL3314443 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL1409549 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL1409552 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL10792875 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL1069060 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Bromide SCHEMBL9510236 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4113 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036659-A | Process for preparing 2-bromobenzofuran derivatives and precursors thereof | 上海凌凯科技股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-4594366-A1 | MODIFIED WATER-SOLUBLE POLYSACCHARIDES HAVING DIFFERENT CATION TYPES FOR SLURRIES IN CHEMICAL MECHANICAL PLANARIZATION | Versum Materials US, LLC (US) | 2025-08-06 | — | — | EP | claimed |
| US-20250215150-A1 | CARBONATE-EPOXY COPOLYMER, CURABLE CARBONATE COMPOSITION, AND MANUFACTURING METHOD OF FORMING CARBONATE-CONTAINING THERMOSET | Swancor Innovation & Incubation Co., Ltd. (TW) | 2025-07-03 | — | — | US | claimed |
| EP-4578889-A1 | CARBONATE-EPOXY COPOLYMER, CURABLE CARBONATE COMPOSITION, AND MANUFACTURING METHOD OF FORMING CARBONATE-CONTAINING THERMOSET | Swancor Innovation & Incubation Co., Ltd. (TW) | 2025-07-02 | — | — | EP | claimed |
| CN-119431243-B | Deuterated huperzine A compound or pharmaceutically acceptable salt thereof as well as preparation method and application thereof | 万邦德制药集团有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-119912788-A | Pultrusion epoxy resin composition and application thereof, epoxy resin material and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-115959963-B | Synthesis method of cis, cis-3, 6, 9-heptadecyltriene | 中国林业科学研究院森林生态环境与自然保护研究所 | 2025-04-25 | — | — | CN | claimed |
| CN-119874801-A | Mitochondrial targeting cholic acid derivative and preparation method and application thereof | 江苏护理职业学院 | 2025-04-25 | — | — | CN | claimed |
| CN-119823528-A | Optical chip packaging material, preparation method and application thereof and LED element | 北京康美特科技股份有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119823483-A | High-heat-resistance glass fiber reinforced polypropylene material and preparation method thereof | 苏州润佳工程塑料股份有限公司 | 2025-04-15 | — | — | CN | claimed |
| WO-1991019724-A2 | PROCESS FOR 2-DEOXYGLUCOSIDES | RHONE-POULENC RORER LIMITED (GB) | 1991-12-26 | — | — | WO | claimed |
| US-5070206-A | INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE; ANTICHOLESTEROL, ANTILIPEMIC | BRISTOL-MYERS COMPANY (US) | 1991-12-03 | — | — | US | claimed |
| US-4939265-A | Intermediates and process for the preparation of antihypercholesterolemic tetrazole compounds | BRISTOL-MYERS COMPANY (US) | 1990-07-03 | — | — | US | claimed |
| WO-1990003841-A1 | TREATMENT OF RHODIUM CATALYSTS | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-04-19 | — | — | WO | claimed |
| EP-0355820-A1 | Antihypercholesterolemic tetrazol-1-yl compounds | Bristol-Myers Squibb Company (US) | 1990-02-28 | — | — | EP | claimed |
| EP-0299034-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS WITH ANTIULCER ACTION. | JANUS FARMA SRL (IT) | 1989-01-18 | — | — | EP | claimed |
| US-4783549-A | Benzonorbornene derivatives, processes for their preparation and medicinal and cosmetic compositions containing them | L'OREAL (FR) | 1988-11-08 | — | — | US | claimed |
| CN-88100993-A | Intermediate of antihypercholesterolemic tetrazole compound and preparation method thereof | BRISTOL MILLS CO (US) | 1988-09-07 | — | — | CN | claimed |
| WO-1988005436-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS WITH ANTIULCER ACTION | JANUS FARMACEUTICI SRL (IT) | 1988-07-28 | — | — | WO | claimed |
| US-4100338-A | Process for preparing solid polymers of norbornadiene | SUN OIL COMPANY OF PENNSYLVANIA (US) | 1978-07-11 | — | — | US | claimed |