SCHEMBL7150601

SCHEMBL7150601

C[C@H](Cc1ccccc1)NC[C@H](O)c1cccc(Cl)c1

nearest known ligand 0.81

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 4/20 0.81
ADRB3 P13945 11/20 0.74
ADRB1 P08588 9/20 0.74
ADRB2 P07550 12/20 0.71
ADRA1D P25100 1/20 0.70
ADRA1A P35348 1/20 0.70
ADRA1B P35368 1/20 0.70
CYP1A2 P05177 1/20 0.70
CYP2D6 P10635 1/20 0.70
CYP2C9 P11712 1/20 0.70
CYP2C19 P33261 1/20 0.70
GLA P06280 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8305207 1.00 SLC2A1 (0.81) SLC2A1ADRB3ADRB1ADRB2ADRA1D
SCHEMBL7150600 1.00 SLC2A1 (0.81) SLC2A1ADRB3ADRB1ADRB2ADRA1D
SCHEMBL10433615 0.95 SLC2A1 (0.78) SLC2A1ADRB3ADRB1ADRB2ADRA1D
SCHEMBL7207154 0.94 ADRB3 (0.81) SLC2A1ADRB3ADRB1ADRB2ADRA1D
SCHEMBL7149376 0.94 ADRB3 (0.81) SLC2A1ADRB3ADRB1ADRB2ADRA1D
SCHEMBL7149375 0.94 ADRB3 (0.81) SLC2A1ADRB3ADRB1ADRB2ADRA1D
SCHEMBL11182206 0.91 SLC2A1 (0.83) SLC2A1ADRB3ADRB1ADRB2ADRA1D
SCHEMBL10772479 0.91 SLC2A1 (0.83) SLC2A1ADRB3ADRB1ADRB2ADRA1D
SCHEMBL10772483 0.91 SLC2A1 (0.83) SLC2A1ADRB3ADRB1ADRB2ADRA1D
SCHEMBL10775119 0.91 SLC2A1 (0.97) SLC2A1ADRB3ADRB1ADRB2ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030143701-A1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. 2003-07-31 US disclosed
EP-0924194-B1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEM (JP) 2003-05-14 EP disclosed
US-6528686-B1 Reacting primary amine and ketone functionalized derivatives; catalytically reducing DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-03-04 US disclosed
EP-0924193-B1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEM (JP) 2003-02-19 EP disclosed
EP-0939134-B1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEM (JP) 2002-09-11 EP disclosed
US-6114582-A DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-05 US disclosed
EP-0654534-B1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEM (JP) 2000-03-01 EP disclosed
EP-0939134-A1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-09-01 EP disclosed
EP-0924193-A1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-06-23 EP disclosed
EP-0924194-A2 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-06-23 EP disclosed
US-5811293-A CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed
US-5629200-A MICROORGANISM DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-05-13 US disclosed
EP-0654534-A2 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-24 EP disclosed