SCHEMBL715220

SCHEMBL715220

C=CC(CCCCC)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.50
FFAR1 O14842 2/20 0.50
MAPT P10636 1/20 0.48
LCK P06239 1/20 0.48
PPARD Q03181 1/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.48
ZDHHC2 Q9UIJ5 1/20 0.48
ACE2 Q9BYF1 1/20 0.46
GRIK1 P39086 2/20 0.43
GRIK2 Q13002 2/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CA2 P00918 1/20 0.42
MAPK1 P28482 1/20 0.42
FFAR4 Q5NUL3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7555468 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL322755 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL322629 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL16670773 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL183801 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL324704 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL322955 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL743054 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL302569 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL322479 0.98 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3448832-B1 WATER RESISTANCE ADDITIVE FOR PARTICULATE AMMONIUM NITRATE-FUEL OIL (ANFO) EXPLOSIVES CLARIANT INT LTD (CH) 2023-08-02 EP claimed
EP-3119821-B1 SECONDARY SUSPENDING AGENT FOR SUSPENSION POLYMERISATION REACTION SYNTHOMER UK LTD (GB) 2018-07-11 EP claimed
EP-2468708-B1 Catalytic decarboxylative cross-ketonisation of aryl- and alkylcarboxylic acids using iron catalysts COGNIS IP MAN GMBH (DE) 2016-11-09 EP claimed
EP-1960443-B1 METHOD OF FREE RADICALLY POLYMERIZING VINYL MONOMERS 3M INNOVATIVE PROPERTIES CO (US) 2012-10-03 EP claimed
EP-2468708-A1 Catalytic decarboxylative cross-ketonisation of aryl- and alkylcarboxylic acids using iron catalysts Cognis IP Management GmbH (DE) 2012-06-27 EP claimed
US-20110144207-A1 ARYL ALKYL CARBOXYLIC ACID SALTS, PROCESS FOR PREPARATION AND DOSAGE FORMS SHASUN CHEMICALS AND DRUGS LIMITED (IN) 2011-06-16 US claimed
EP-2323976-A1 ARYL ALKYL CARBOXYLIC ACID SALTS, PROCESS FOR PREPARATION AND DOSAGE FORMS Shasun Chemicals And Drugs Limited (IN) 2011-05-25 EP claimed
WO-2011001228-A1 ARYL ALKYL CARBOXYLIC ACID SALTS, PROCESS FOR PREPARATION AND DOSAGE FORMS SHASUN CHEMICALS AND DRUGS LIMITED (IN) 2011-01-06 WO claimed
EP-1800150-B1 WETTABLE HYDROGELS COMPRISING REACTIVE, HYDROPHILIC, POLYMERIC INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE (US) 2008-08-06 EP claimed
EP-1303512-B1 PROCESS FOR PREPARING ARYLACETYLAMINOTHIAZOLES BRISTOL MYERS SQUIBB CO (US) 2005-07-20 EP claimed
JP-2004505079-A 2004-02-19 JP claimed
US-20030216440-A1 Process for preparing arylacetylaminothiazoles CHEN BANG-CHI (US) 2003-11-20 US claimed
EP-1303512-A1 PROCESS FOR PREPARING ARYLACETYLAMINOTHIAZOLES Bristol-Myers Squibb Company (US) 2003-04-23 EP claimed
US-20020072609-A1 Process for preparing arylacetylaminothiazoles CHEN BANG-CHI (US) 2002-06-13 US claimed
US-6392053-B2 INCLUDES REACTING HALOARYLACETIC ACIDS OR ESTERS WITH OLEFINS TO GIVEN VINYLACRYLACETIC ACIDS OR ESTERS, FOLLOWED BY OXIDATION TO FORM THE FORMYLARYLACETIC ACID INTERMEDIATE; CYCLIN DEPENDENT KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2002-05-21 US claimed
WO-2002010161-A1 PROCESS FOR PREPARING ARYLACETYLAMINOTHIAZOLES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-02-07 WO claimed
US-20010004639-A1 Process for preparing arylacetylaminothiazoles BRISTOL-MYERS SQUIBB COMPANY 2001-06-21 US claimed
JP-9234368-A None JP disclosed
JP-H09234368-A NOVEL SOLID CATALYST CONTAINING RUTHENIUM AND TIN AND PREPARATION OF ARYL ALKYL ALCOHOL USING THE SAME KAWAKEN FINE CHEM CO LTD 1997-09-09 JP disclosed
US-3946054-A PERFUMES, TOBACCO, FOOD FLAVORS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216440-A1 Process for preparing arylacetylaminothiazoles CCNI, CCNT1, CCNA1 GPR84 3012/4885FFAR1 1426/4885MAPT 4542/4885
US-20020072609-A1 Process for preparing arylacetylaminothiazoles CCNT1, CCNI, CCNA1 GPR84 2320/4885FFAR1 1187/4885MAPT 4688/4885
US-20010004639-A1 Process for preparing arylacetylaminothiazoles CCNI, CCNA1, CCNT1 GPR84 2780/4885FFAR1 1401/4885MAPT 4514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.