Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450396 | 0.89 | EPHX1 (0.50) | EPHX1LMNAPOLBUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11412369 | 0.84 | EPHX1 (0.46) | EPHX1LMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL27454583 | 0.82 | LMNA (0.40) | EPHX1LMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL3684347 | 0.81 | EPHX1 (0.60) | EPHX1LMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL15822139 | 0.81 | EPHX1 (0.48) | EPHX1LMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL13294283 | 0.81 | EPHX1 (0.60) | EPHX1LMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL970008 | 0.80 | — | — | |
| SCHEMBL18864356 | 0.80 | — | — | |
| SCHEMBL11412372 | 0.80 | EPHX1 (0.43) | EPHX1LMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL969836 | 0.78 | EPHX1 (0.47) | EPHX1LMNAPOLBUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080411-A2 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND COMPOSITIONS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2004-09-23 | — | — | WO | disclosed |