Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6295669 | 0.98 | GPR3 (0.32) | GPR3HTR2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8679648 | 0.98 | GPR3 (0.33) | GPR3HTR2ACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL6295671 | 0.95 | GPR3 (0.32) | GPR3HTR2ACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL6727344 | 0.95 | GPR3 (0.32) | GPR3HTR2ACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL6727342 | 0.95 | CYP3A4 (0.34) | GPR3HTR2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7158610 | 0.89 | USP2 (0.33) | GPR3HTR2ACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL6731375 | 0.88 | USP2 (0.33) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL8609627 | 0.88 | USP2 (0.36) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL8362300 | 0.87 | USP2 (0.34) | GPR3HTR2ACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL6294799 | 0.86 | USP2 (0.35) | ACHECHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534609-B2 | Making by combining an organoaluminoxane and a metallocene having olefinic unsaturated substituent(s) in an aliphatic liquid, prepolymerizing olefin(s) to produce a prepolymerized solid catalyst and separating from the liquid | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2003-03-18 | — | — | US | claimed |
| EP-0685495-B1 | Method for using a supported metallocene catalyst system | PHILLIPS PETROLEUM CO (US) | 1998-04-08 | — | — | EP | claimed |