Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 5/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 10/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7154058 | 0.98 | F3 (0.40) | F3F10F7PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7152683 | 0.94 | F3 (0.43) | F3F10F7F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL7153347 | 0.92 | F3 (0.47) | F3F10F7F2TMPRSS6 | |
| SCHEMBL7153138 | 0.90 | PRSS1 (0.38) | F10PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7154637 | 0.87 | F2 (0.40) | F3F10F7PRSS1PRSS2 | |
| SCHEMBL7152685 | 0.84 | F2 (0.37) | F3F10F7PRSS1PRSS2 | |
| SCHEMBL7153348 | 0.82 | F10 (0.42) | F3F10F7F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL7156674 | 0.82 | PRSS1 (0.61) | F3F10F7PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7151221 | 0.81 | ST14 (0.62) | F10PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7151889 | 0.80 | F2 (0.51) | F3PRSS1PRSS2PRSS3ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |