Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7153927 | 0.93 | F2 (0.49) | F2PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7151221 | 0.92 | ST14 (0.62) | F2PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7154700 | 0.91 | ALDH1A1 (0.58) | F2ALDH1A1F3 | |
| Trifluoroacetic Acid SCHEMBL7158302 | 0.89 | F2 (0.59) | F2PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7152762 | 0.89 | ALDH1A1 (0.47) | F2PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7156674 | 0.88 | PRSS1 (0.61) | F2PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7157168 | 0.87 | MGAT2 (0.50) | F2PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7152732 | 0.87 | F10 (0.47) | F2PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7153324 | 0.86 | F2 (0.48) | F2PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7150783 | 0.85 | PRSS1 (0.58) | F2PRSS1PRSS2PRSS3ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |