⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285592 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL2522703 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL7081474 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL8741526 | 0.81 | TSHR (0.30) | — | |
| Hydrochloric Acid SCHEMBL2951043 | 0.80 | — | — | |
| SCHEMBL313598 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL19930034 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL9887659 | 0.75 | — | — | |
| SCHEMBL26653603 | 0.73 | — | — | |
| SCHEMBL26630548 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139000-A1 | METHOD FOR PRODUCING 2' MODIFIED PYRIMIDINE NUCLEOSIDE | NISSAN CHEMICAL CORPORATION (JP) | 2026-05-21 | — | — | US | disclosed |
| WO-2024190907-A1 | PRODUCTION METHODS FOR 2'-O-MODIFIED ADENOSINE PHOSPHORAMIDITE AND INTERMEDIATE THEREOF | 日産化学株式会社 | 2024-09-19 | — | — | WO | disclosed |
| EP-4410803-A1 | METHOD FOR PRODUCING 2' MODIFIED PYRIMIDINE NUCLEOSIDE | Nissan Chemical Corporation (JP) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023027065-A1 | METHOD FOR PRODUCING 2'-MODIFIED GUANOSINE COMPOUND | 日産化学株式会社 | 2023-03-02 | — | — | WO | disclosed |
| US-6528631-B1 | Folates are conjugated to an oligonucleotide including at the 2'-, 3'-, 5'-, nucleobase and internucleotide linkage sites; improved transfer across cellular membranes; regioselective synthesis | ISIS PHARMACEUTICALS, INC. | 2003-03-04 | — | — | US | disclosed |