Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081474 | 0.85 | TSHR (0.30) | TSHR | |
| SCHEMBL7153188 | 0.81 | — | — | |
| SCHEMBL313598 | 0.81 | TSHR (0.31) | TSHR | |
| SCHEMBL204034 | 0.80 | TSHR (0.32) | TSHR | |
| SCHEMBL29674430 | 0.78 | TSHR (0.31) | TSHR | |
| Ammonia Solution, Strong SCHEMBL21828798 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL20211370 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL30389839 | 0.74 | TSHR (0.34) | TSHR | |
| SCHEMBL10169834 | 0.74 | — | — | |
| SCHEMBL24487862 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617279-A1 | MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME | Luxna Biotech Co., Ltd. (JP) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024190907-A1 | PRODUCTION METHODS FOR 2'-O-MODIFIED ADENOSINE PHOSPHORAMIDITE AND INTERMEDIATE THEREOF | 日産化学株式会社 | 2024-09-19 | — | — | WO | disclosed |
| EP-3862431-B1 | METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES | TORAY INDUSTRIES (JP) | 2024-06-26 | — | — | EP | disclosed |
| WO-2024101446-A1 | MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME | ルクサナバイオテク株式会社 | 2024-05-16 | — | — | WO | disclosed |
| US-20240110186-A1 | METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES | TORAY INDUSTRIES, INC. (JP) | 2024-04-04 | — | — | US | disclosed |
| US-11891602-B2 | Method of producing hairpin single-stranded RNA molecules | TORAY INDUSTRIES, INC. (JP) | 2024-02-06 | — | — | US | disclosed |
| WO-2023027065-A1 | METHOD FOR PRODUCING 2'-MODIFIED GUANOSINE COMPOUND | 日産化学株式会社 | 2023-03-02 | — | — | WO | disclosed |
| US-11518994-B2 | Artificial single guide RNA and use thereof | BONAC CORPORATION (JP) | 2022-12-06 | — | — | US | disclosed |
| EP-3276003-B1 | SINGLE-CHAIN NUCLEIC ACID MOLECULE HAVING DELIVERY FUNCTION AND GENE EXPRESSION CONTROL ABILITY | BONAC CORP (JP) | 2022-07-20 | — | — | EP | disclosed |
| US-20210317495-A1 | METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES | TORAY INDUSTRIES, INC. (JP) | 2021-10-14 | — | — | US | disclosed |
| US-8993738-B2 | Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom | ISIS PHARMACEUTICALS, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| WO-2014205451-A2 | COMPOSITIONS AND METHODS FOR MODULATION OF TARGET NUCLEIC ACIDS | ISIS PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |
| US-20130237697-A1 | BUILDING BLOCKS AND METHODS FOR THE SYNTHESIS OF 5-HYDROXYMETHYLCYTOSINE-CONTAINING NUCLEIC ACIDS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2013-09-12 | — | — | US | disclosed |
| EP-2601204-A2 | MODIFIED NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | Isis Pharmaceuticals, Inc. (US) | 2013-06-12 | — | — | EP | disclosed |
| US-20130084576-A1 | MODIFIED NUCLEOSIDES, ANALOGS THEREOF AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 2013-04-04 | — | — | US | disclosed |
| WO-2011139702-A2 | MODIFIED NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| US-8039611-B2 | 2′-hydroxyl group-modified ribonucleoside derivatives | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20100016574-A1 | 2'-Hydroxyl Group-Modified Ribonucleoside Derivatives | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2006293-A9 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-2006293-A2 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | Tokyo Institute of Technology (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130084576-A1 | MODIFIED NUCLEOSIDES, ANALOGS THEREOF AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | RNMT, HNRNPM, NOP2 | TSHR 4513/4885 |
| US-11518994-B2 | Artificial single guide RNA and use thereof | SLIRP, TRDMT1, RNASEL | TSHR 1000/4885 |
| US-20130237697-A1 | BUILDING BLOCKS AND METHODS FOR THE SYNTHESIS OF 5-HYDROXYMETHYLCYTOSINE-CONTAINING NUCLEIC ACIDS | RNGTT, NSUN2, NT5C3B | TSHR 3779/4885 |
| US-20100016574-A1 | 2'-Hydroxyl Group-Modified Ribonucleoside Derivatives | RNASEH1, RNASEL, NSUN2 | TSHR 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.