Ethylene

Ethylene

SCHEMBL715322

C=C.O=C(O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.80
CES2 O00748 2/20 0.64
CES1 P23141 2/20 0.64
EPHX2 P34913 2/20 0.61
RXRA P19793 1/20 0.60
RXRB P28702 1/20 0.60
RXRG P48443 1/20 0.60
CYP2C8 P10632 1/20 0.59
TP53 P04637 1/20 0.55
TSHR P16473 1/20 0.55
GSK3B P49841 2/20 0.53
PTPN1 P18031 2/20 0.53
NR4A1 P22736 1/20 0.53
NR4A2 P43354 1/20 0.53
NR4A3 Q92570 1/20 0.53
MAP4K4 O95819 1/20 0.50
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78879 0.95 SRD5A2 (0.87) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL1330891 0.95 SRD5A2 (0.87) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL1042428 0.93 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
Water SCHEMBL28138640 0.93 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL6762584 0.93 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL23521062 0.93 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL29208531 0.93 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
Hydrochloric Acid SCHEMBL8432890 0.93 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
Ethane SCHEMBL10971565 0.91 SRD5A2 (0.80) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL2766437 0.89 SRD5A2 (1.00) SRD5A2CES2CES1EPHX2RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120235148-A1 PHOTO-CROSSLINKABLE MATERIAL FOR ORGANIC THIN FILM TRANSISTOR INSULATING LAYER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-20 US disclosed
EP-2479791-A1 PHOTO-CROSSLINKABLE MATERIAL FOR ORGANIC THIN FILM TRANSISTOR INSULATING LAYER Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120053287-A1 RESIN COMPOSITION FOR INSULATING LAYER SUMITOMO CHEMICAL COMPANY, LTD (JP) 2012-03-01 US disclosed