SCHEMBL78879

SCHEMBL78879

O=C(O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.87

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.87
CES2 O00748 2/20 0.70
CES1 P23141 2/20 0.70
EPHX2 P34913 1/20 0.65
RXRA P19793 1/20 0.64
RXRB P28702 1/20 0.64
RXRG P48443 1/20 0.64
CYP2C8 P10632 1/20 0.62
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
GSK3B P49841 2/20 0.57
PTPN1 P18031 2/20 0.57
NR4A1 P22736 1/20 0.57
NR4A2 P43354 1/20 0.57
NR4A3 Q92570 1/20 0.57
MAP4K4 O95819 1/20 0.53
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1330891 1.00 SRD5A2 (0.87) SRD5A2CES2CES1EPHX2RXRA
Hydrochloric Acid SCHEMBL8432890 0.98 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
Water SCHEMBL28138640 0.98 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL6762584 0.98 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL1042428 0.98 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL23521062 0.98 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL29208531 0.98 SRD5A2 (0.83) SRD5A2CES2CES1EPHX2RXRA
Ethane SCHEMBL10971565 0.95 SRD5A2 (0.80) SRD5A2CES2CES1EPHX2RXRA
Ethylene SCHEMBL715322 0.95 SRD5A2 (0.80) SRD5A2CES2CES1EPHX2RXRA
SCHEMBL505133 0.93 SRD5A2 (0.77) SRD5A2CES2CES1EPHX2RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3037 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120924880-B High-strength wear-resistant alloy steel for track shoes and preparation method thereof Jiangxi Depu Mining Equipment Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12593844-B2 Method and compounds to induce plant tolerance against arthropod pests VIB VZW (BE) 2026-04-07 US claimed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
WO-2025202864-A1 ENT1 INHIBITORS IN COMBINATION WITH ONCOLYTIC VIRUSES AND THEIR USE IN THE TREATMENT OF CANCER iTeos Belgium SA (BE) 2025-10-02 WO claimed
WO-2025126110-A1 ENT1 INHIBITORS IN COMBINATION WITH BISPECIFIC ANTIBODIES iTeos Belgium SA (BE) 2025-06-19 WO claimed
EP-4559009-A2 PARTICLES Life Technologies AS (NO) 2025-05-28 EP claimed
WO-2025104613-A1 ENT1 INHIBITORS IN COMBINATION WITH CHECKPOINT INHIBITORS iTeos Belgium SA (BE) 2025-05-22 WO claimed
US-20250161908-A1 Tailored nanoporous sorbents for rapid, noninvasive disease detection NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2025-05-22 US claimed
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120020115-A Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN claimed
EP-0612734-A1 Novel orally active antifungal agents J. URIACH & CIA. S.A. (ES) 1994-08-31 EP claimed
US-5219477-A Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid THE DOW CHEMICAL COMPANY (US) 1993-06-15 US claimed
US-5011932-A Anthelmintic pyridinyl acylhydrazones derivatives UPJOHN COMPANY (US) 1991-04-30 US claimed
US-4780319-A DRUG DELIVERY USING POLYORTHOESTERS COATINGS MERCK & CO., INC. (US) 1988-10-25 US claimed
EP-0214158-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1987-03-18 EP claimed
WO-1986004582-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1986-08-14 WO claimed
EP-0015824-B1 METAL DITHIOPHOSPHATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ADDITIVES FOR LUBRICATING OILS OROGIL (FR) 1982-02-17 EP claimed
US-4288335-A REACTING ESTER WITH PHOSPHORUS SULFIDE, METAL OXIDE OROGIL (FR) 1981-09-08 US claimed
US-4161598-A ANALGESICS, NARCOTIC ANTAGONISTS STERLING DRUG INC. (US) 1979-07-17 US claimed
US-4005145-A ISOMERIZATION OF A,B-UNSATURATED OXO COMPOUNDS TO B,G-ISOMER HOFFMANN-LA ROCHE INC. (US) 1977-01-25 US claimed