SCHEMBL7153238

SCHEMBL7153238

O=C(OCC1COCO1)OCC1COCO1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MGLL Q99685 3/20 0.35
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18030278 0.91 ALDH1A1 (0.45) ALDH1A1TP53CYP3A4IRAK4
SCHEMBL12234441 0.89 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MGLLLMNA
SCHEMBL12234443 0.89 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MGLLIRAK4
SCHEMBL18691824 0.86 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MGLLLMNA
SCHEMBL12234487 0.86 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MGLL
SCHEMBL1834660 0.85 ALDH1A1 (0.35) ALDH1A1TP53CYP3A4
SCHEMBL1834656 0.85 ALDH1A1 (0.35) ALDH1A1TP53CYP3A4
SCHEMBL377540 0.84 ALDH1A1 (0.57) ALDH1A1TP53CYP3A4MGLL
SCHEMBL16244518 0.84 ALDH1A1 (0.42) ALDH1A1TP53CYP3A4MGLLLMNA
SCHEMBL21804854 0.84 ALDH1A1 (0.47) ALDH1A1TP53CYP3A4MGLLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1289977-A2 TRITERPENOID DERIVATIVES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS Univerzita palackeho V Olomouci (CZ) 2003-03-12 EP disclosed
WO-2001090096-A2 TRITERPENOID DERIVATIVES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2001-11-29 WO disclosed