Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 4/20 | 0.40 |
| ▸ | AXL | P30530 | 3/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152990 | 0.89 | MAPKAPK2 (0.38) | APPBCHEACHEMERTKAXL | |
| SCHEMBL7152982 | 0.89 | MAPKAPK2 (0.38) | APPBCHEACHEMERTKAXL | |
| Hydrochloric Acid SCHEMBL4889999 | 0.89 | PI4KA (0.42) | APPBCHEACHEMERTKAXL | |
| Hydrochloric Acid SCHEMBL4889988 | 0.89 | PI4KA (0.42) | APPBCHEACHEMERTKAXL | |
| Hydrochloric Acid SCHEMBL4901100 | 0.88 | MAPKAPK2 (0.38) | APPBCHEACHEMERTKAXL | |
| Hydrochloric Acid SCHEMBL4901111 | 0.88 | MAPKAPK2 (0.38) | APPBCHEACHEMERTKAXL | |
| SCHEMBL7153615 | 0.85 | PIM1 (0.38) | BTKCDK1CCNB1CCNB2CCNB3 | |
| SCHEMBL7154151 | 0.84 | PIM1 (0.38) | MERTKAXLTYRO3BTKMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL4898599 | 0.84 | PIM1 (0.38) | BTKCDK1CCNB1CCNB2CCNB3 | |
| SCHEMBL7154149 | 0.84 | PIM1 (0.38) | MERTKAXLTYRO3BTKMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347975-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | Aventis Pharma S.A. (FR) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002051843-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | disclosed |