Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154329 | 1.00 | ADRB1 (0.50) | ADRB1ADRB3ADRB2SIGMAR1KDM1A | |
| SCHEMBL11088887 | 0.90 | ADRB1 (0.54) | ADRB1ADRB3ADRB2SIGMAR1KDM1A | |
| SCHEMBL7152845 | 0.90 | ADRB1 (0.54) | ADRB1ADRB3ADRB2SIGMAR1KDM1A | |
| SCHEMBL7152844 | 0.90 | ADRB1 (0.54) | ADRB1ADRB3ADRB2SIGMAR1KDM1A | |
| Hydrochloric Acid SCHEMBL11084224 | 0.89 | ADRB1 (0.53) | ADRB1ADRB3ADRB2SIGMAR1KDM1A | |
| SCHEMBL7148280 | 0.87 | ADRB1 (0.51) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7146992 | 0.87 | ADRB1 (0.51) | ADRB1ADRB3ADRB2SIGMAR1KDM1A | |
| SCHEMBL7148275 | 0.87 | ADRB1 (0.51) | ADRB1ADRB3ADRB2 | |
| SCHEMBL11088831 | 0.87 | ADRB1 (0.51) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7146988 | 0.87 | ADRB1 (0.51) | ADRB1ADRB3ADRB2SIGMAR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030143701-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. | 2003-07-31 | — | — | US | disclosed |
| US-6528686-B1 | Reacting primary amine and ketone functionalized derivatives; catalytically reducing | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-0924193-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-02-19 | — | — | EP | disclosed |
| US-6114582-A | DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0654534-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2000-03-01 | — | — | EP | disclosed |
| EP-0939134-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0924193-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0924194-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5629200-A | MICROORGANISM | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0654534-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-24 | — | — | EP | disclosed |