Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.37 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | YES1 | P07947 | 2/20 | 0.37 |
| ▸ | LYN | P07948 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | HCK | P08631 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | BCR | P11274 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715448 | 1.00 | SRC (0.40) | SRCPIK3R2DRD2DRD3PKMYT1 | |
| SCHEMBL715848 | 0.88 | PIK3R2 (0.40) | PIK3R2HTR2AHTR2CKCNH2SLC6A4 | |
| SCHEMBL718468 | 0.88 | PIK3R2 (0.40) | PIK3R2HTR2AHTR2CKCNH2SLC6A4 | |
| SCHEMBL720791 | 0.88 | PIK3CD (0.40) | SRCDRD2DRD3LCKLYN | |
| SCHEMBL720792 | 0.88 | PIK3CD (0.40) | SRCDRD2DRD3LCKLYN | |
| SCHEMBL714861 | 0.85 | PIK3CD (0.42) | PIK3R2CNR2CNR1PIK3CD | |
| SCHEMBL714860 | 0.85 | PIK3CD (0.42) | PIK3R2CNR2CNR1PIK3CD | |
| SCHEMBL716959 | 0.85 | PIK3CB (0.39) | PIK3R2PIK3CDCYP3A4CYP2C9PIK3CA | |
| SCHEMBL17530783 | 0.83 | KDM4E (0.38) | SRCKITHTR2AFLT3HTT | |
| SCHEMBL15875804 | 0.83 | PIK3CA (0.39) | PIK3R2CNR2CNR1PIK3CDJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |
| US-8785628-B2 | Triazine derivatives as kinase inhibitors | UCB PHARMA, S.A. (BE) | 2014-07-22 | — | — | US | claimed |
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | disclosed |
| US-8785628-B2 | Triazine derivatives as kinase inhibitors | UCB PHARMA, S.A. (BE) | 2014-07-22 | — | — | US | disclosed |
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | UCB PHARMA, S.A. (BE) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | MAP3K15, PI4KA, MAP3K20 | SRC 509/4885PIK3R2 93/4885DRD2 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.