Cyclohexane

Cyclohexane

SCHEMBL7154706

C1CCCCC1.C=CCc1ccccc1OC(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 2/20 0.47
ELANE P08246 1/20 0.44
ADRB2 P07550 3/20 0.44
ADRB1 P08588 3/20 0.44
LMNA P02545 2/20 0.44
HTR1A P08908 2/20 0.44
ADRA2C P18825 2/20 0.44
ADRB3 P13945 1/20 0.44
SLC6A2 P23975 1/20 0.44
BDKRB2 P30411 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
HTR2B P41595 1/20 0.44
KCNH2 Q12809 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
PMP22 Q01453 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861238 0.95 KDM4E (0.51) KDM4EALDH1A1ELANEADRB2ADRB1
SCHEMBL278521 0.83 KDM4E (0.49) KDM4EALDH1A1ELANEADRB2ADRB1
SCHEMBL7157956 0.83 KDM4E (0.49) KDM4EALDH1A1ELANEADRB2ADRB1
SCHEMBL29056747 0.83 KDM4E (0.44) KDM4EALDH1A1ELANEADRB2ADRB1
SCHEMBL7157959 0.82 KDM4E (0.52) KDM4EALDH1A1ELANEADRB2ADRB1
SCHEMBL5448543 0.81 KDM4E (0.48) KDM4EALDH1A1ELANEADRB2ADRB1
SCHEMBL31112136 0.81 ESR1 (0.50) KDM4EALDH1A1ELANEADRB2ADRB1
SCHEMBL5179050 0.81 GABRA1 (0.42) KDM4EALDH1A1ELANETDP1KMT2A
SCHEMBL31112624 0.81 KMT2A (0.58) KDM4EALDH1A1ELANEADRB2ADRB1
SCHEMBL4284963 0.81 KMT2A (0.58) KDM4EALDH1A1ELANEADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1013177-B1 A game-type flavouring agent. NESTLE SA (CH) 2003-09-03 EP claimed