Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 7/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 3/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 3/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | PRKACA | P17612 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.31 |
| ▸ | CLK2 | P49760 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | PRKX | P51817 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154800 | 1.00 | PIM1 (0.44) | PIM1IRAK4BTKSMYD3CCNB2 | |
| Hydrochloric Acid SCHEMBL4898576 | 0.99 | PIM1 (0.43) | PIM1IRAK4BTKSMYD3CCNB2 | |
| Hydrochloric Acid SCHEMBL4898566 | 0.99 | PIM1 (0.43) | PIM1IRAK4BTKSMYD3CCNB2 | |
| SCHEMBL7153609 | 0.79 | PIM1 (0.38) | PIM1IRAK4BTKSMYD3CCNB2 | |
| SCHEMBL7153615 | 0.79 | PIM1 (0.38) | PIM1IRAK4BTKSMYD3CCNB2 | |
| Hydrochloric Acid SCHEMBL4898584 | 0.78 | PIM1 (0.38) | PIM1IRAK4BTKSMYD3CCNB2 | |
| SCHEMBL7154149 | 0.78 | PIM1 (0.38) | PIM1IRAK4BTKSMYD3CCNB2 | |
| Hydrochloric Acid SCHEMBL4898599 | 0.78 | PIM1 (0.38) | PIM1IRAK4BTKSMYD3CCNB2 | |
| SCHEMBL7154151 | 0.78 | PIM1 (0.38) | PIM1IRAK4BTKSMYD3CCNB2 | |
| Hydrochloric Acid SCHEMBL4898605 | 0.77 | PIM1 (0.37) | PIM1IRAK4BTKSMYD3CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347975-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | Aventis Pharma S.A. (FR) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002051843-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | disclosed |