Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 5/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | PRKCG | P05129 | 2/20 | 0.39 |
| ▸ | PRKCB | P05771 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | PRKCH | P24723 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155014 | 1.00 | CES2 (0.50) | CES2THRBGMNNTP53POLB | |
| SCHEMBL7156443 | 1.00 | CES2 (0.50) | CES2THRBGMNNTP53POLB | |
| SCHEMBL7155018 | 1.00 | CES2 (0.50) | CES2THRBGMNNTP53POLB | |
| SCHEMBL7158833 | 1.00 | CES2 (0.50) | CES2THRBGMNNTP53POLB | |
| SCHEMBL7153252 | 1.00 | CES2 (0.50) | CES2THRBGMNNTP53POLB | |
| SCHEMBL23034315 | 0.97 | CES2 (0.54) | CES2THRBGMNNTP53POLB | |
| SCHEMBL7153602 | 0.97 | CES2 (0.54) | CES2THRBGMNNTP53POLB | |
| Dioctylsulfane SCHEMBL1358875 | 0.97 | CES2 (0.54) | CES2THRBGMNNTP53POLB | |
| SCHEMBL200096 | 0.97 | CES2 (0.54) | CES2THRBGMNNTP53POLB | |
| SCHEMBL199887 | 0.97 | CES2 (0.54) | CES2THRBGMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866049-B1 | Chlorination of aromatic compounds and catalysts therefor | UNIV WALES SWANSEA (GB) | 2003-11-19 | — | — | EP | claimed |
| EP-0866049-B1 | Chlorination of aromatic compounds and catalysts therefor | UNIV WALES SWANSEA (GB) | 2003-11-19 | — | — | EP | disclosed |
| EP-0866049-A2 | Chlorination of aromatic compounds and catalysts therefor | The University of Wales Swansea (GB) | 1998-09-23 | — | — | EP | disclosed |