Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156742 | 1.00 | TRPA1 (0.50) | TRPA1TDP1FOLH1CA2ALDH1A1 | |
| SCHEMBL7153640 | 1.00 | TRPA1 (0.50) | TRPA1TDP1FOLH1CA2ALDH1A1 | |
| SCHEMBL7156424 | 1.00 | — | — | |
| SCHEMBL7155535 | 1.00 | TRPA1 (0.50) | TRPA1TDP1FOLH1CA2ALDH1A1 | |
| SCHEMBL11965847 | 1.00 | TRPA1 (0.50) | TRPA1TDP1FOLH1CA2ALDH1A1 | |
| SCHEMBL7155007 | 1.00 | TRPA1 (0.50) | TRPA1TDP1FOLH1CA2ALDH1A1 | |
| SCHEMBL2395916 | 0.95 | — | — | |
| SCHEMBL1866041 | 0.89 | TRPA1 (0.44) | TRPA1TDP1CA2 | |
| SCHEMBL19982398 | 0.89 | TRPA1 (0.44) | TRPA1TDP1CA2 | |
| SCHEMBL862798 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866049-B1 | Chlorination of aromatic compounds and catalysts therefor | UNIV WALES SWANSEA (GB) | 2003-11-19 | — | — | EP | claimed |
| EP-0866049-B1 | Chlorination of aromatic compounds and catalysts therefor | UNIV WALES SWANSEA (GB) | 2003-11-19 | — | — | EP | disclosed |
| EP-0866049-A2 | Chlorination of aromatic compounds and catalysts therefor | The University of Wales Swansea (GB) | 1998-09-23 | — | — | EP | disclosed |