Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526383 | 0.86 | MAPT (0.58) | MAPTALDH1A1LMNAADRA2AADRA2B | |
| SCHEMBL11020309 | 0.84 | MAPT (0.50) | MAPTALDH1A1LMNAADRA2AADRA2B | |
| SCHEMBL1241959 | 0.84 | ABL1 (0.56) | MAPTALDH1A1PRSS1F2PRSS2 | |
| Hydrochloric Acid SCHEMBL9181167 | 0.83 | MAPT (0.56) | MAPTALDH1A1LMNAADRA2AADRA2B | |
| SCHEMBL19272209 | 0.82 | ADRA2A (0.47) | MAPTALDH1A1PRSS1F2PRSS2 | |
| SCHEMBL11498100 | 0.82 | ABL1 (0.59) | MAPTALDH1A1PRSS1F2PRSS2 | |
| SCHEMBL187892 | 0.82 | ABL1 (0.59) | MAPTALDH1A1PRSS1F2PRSS2 | |
| SCHEMBL9506930 | 0.82 | ABL1 (0.59) | MAPTALDH1A1PRSS1F2PRSS2 | |
| SCHEMBL2720066 | 0.82 | ABL1 (0.59) | MAPTALDH1A1PRSS1F2PRSS2 | |
| SCHEMBL3395174 | 0.82 | ABL1 (0.59) | MAPTALDH1A1PRSS1F2PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6530960-B1 | Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades | L'OREAL S.A. (FR) | 2003-03-11 | — | — | US | claimed |
| US-5869692-A | COUPLER FOR OXIDATION COLOR DYEING OF HAIR | L'OREAL (FR) | 1999-02-09 | — | — | US | disclosed |
| US-5704948-A | Compositions for dyeing keratinous fibers and keratinous fiber dyeing processes with derivatives of 4-hydroxyindole and oxidation bases | L'OREAL (FR) | 1998-01-06 | — | — | US | disclosed |