Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165976 | 0.94 | — | — | |
| SCHEMBL365078 | 0.94 | TSHR (0.39) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ethylene Glycol SCHEMBL27789603 | 0.91 | TSHR (0.37) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL27982511 | 0.91 | — | — | |
| SCHEMBL27633149 | 0.91 | — | — | |
| SCHEMBL27863295 | 0.91 | — | — | |
| Ethylene Glycol SCHEMBL27508413 | 0.91 | TSHR (0.37) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Isopropyl Alcohol SCHEMBL8328019 | 0.88 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Isopropyl Alcohol SCHEMBL14895288 | 0.88 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ethylene Glycol SCHEMBL27888510 | 0.86 | HSD17B10 (0.39) | ALDH1A1TSHRMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066235-B1 | SYNTHETIC ENDOGENOUS CANNABINOID ANALOGUES AND USES THEREOF | YISSUM RES DEV CO (IL) | 2003-10-01 | — | — | EP | claimed |
| EP-2771920-A1 | SOLUTION-PROCESSABLE TUNGSTEN OXIDE BUFFER LAYERS AND ORGANIC ELECTRONICS COMPRISING SAME | nanograde AG (CH) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013059948-A1 | SOLUTION-PROCESSABLE TUNGSTEN OXIDE BUFFER LAYERS AND ORGANIC ELECTRONICS COMPRISING SAME | NANOGRADE AG (CH) | 2013-05-02 | — | — | WO | disclosed |