Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154235 | 1.00 | CA2 (0.38) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL4489089 | 0.84 | CA2 (0.39) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL4489093 | 0.84 | CA2 (0.39) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL4489086 | 0.84 | CA2 (0.39) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL591538 | 0.82 | CA2 (0.40) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL10249454 | 0.82 | CA2 (0.40) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL591537 | 0.82 | CA2 (0.40) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL591536 | 0.82 | CA2 (0.40) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL26322303 | 0.82 | CA2 (0.40) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL13631758 | 0.80 | CA2 (0.36) | CA2TBXA2RTMEM97SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541647-B2 | Active materials; drugs; antiinflammatory agents; antiallergens | MILLENNIUM PHARMACEUTICALS, INC. | 2003-04-01 | — | — | US | disclosed |
| US-6310221-B1 | PREPARING A 4-FLUOROPHENOXYMETHYL-(HYDROXY)-TETRAHYDROFURAN BY REACTING 4-FLUOROPHENOL AND AN EPOXY COMPOUND; REACTING THE EPOXY-PHENYL ETHER WITH AN ACTIVE METHYLENE COMPOUND TO FORM A LACTONE; AND REDUCING THE LACTONE | MILLENNIUM PHARMACEUTICALS, INC. | 2001-10-30 | — | — | US | disclosed |
| EP-1102759-A1 | METHODS FOR SYNTHESIS OF SUBSTITUTED TETRAHYDROFURAN COMPOUND | Millennium Pharmaceuticals, Inc. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000001683-A1 | METHODS FOR SYNTHESIS OF SUBSTITUTED TETRAHYDROFURAN COMPOUND | LEUKOSITE, INC. (US) | 2000-01-13 | — | — | WO | disclosed |