Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154081 | 0.71 | NR4A1 (0.35) | — | |
| SCHEMBL13833298 | 0.62 | PDE10A (0.36) | PDE10A | |
| SCHEMBL27564069 | 0.61 | PDE10A (0.45) | PDE10A | |
| SCHEMBL3208621 | 0.59 | PDE10A (0.42) | PDE10A | |
| SCHEMBL7193572 | 0.57 | PDE10A (0.45) | PDE10A | |
| SCHEMBL8052575 | 0.57 | PDE10A (0.45) | PDE10A | |
| SCHEMBL10407217 | 0.57 | PDE10A (0.45) | PDE10A | |
| SCHEMBL23374062 | 0.56 | IDH2 (0.39) | — | |
| Ammonia Solution, Strong SCHEMBL29008312 | 0.55 | PDE10A (0.43) | PDE10A | |
| SCHEMBL31387261 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347975-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | Aventis Pharma S.A. (FR) | 2003-10-01 | — | — | EP | claimed |
| WO-2002051843-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | claimed |