Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157428 | 0.71 | MAPK6 (0.39) | KDM1AMEN1KMT2A | |
| SCHEMBL7157418 | 0.71 | MAPK6 (0.39) | KDM1AMEN1KMT2A | |
| SCHEMBL7156619 | 0.71 | PDE10A (0.30) | — | |
| Hydrochloric Acid SCHEMBL4897810 | 0.70 | MAPK6 (0.38) | KDM1AMEN1KMT2A | |
| SCHEMBL16649499 | 0.64 | RAB9A (0.52) | NR4A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL2177922 | 0.63 | RAB9A (0.51) | GAAL3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL8598760 | 0.61 | KDM1A (0.55) | KDM1AHTR2CMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17729977 | 0.61 | KDM1A (0.55) | KDM1AHTR2CMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14686148 | 0.61 | RAB9A (0.40) | GAAMEN1KMT2ARAB9AMAPK8 | |
| SCHEMBL16404477 | 0.61 | PDE5A (0.66) | KDM1AL3MBTL1MEN1KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347975-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | Aventis Pharma S.A. (FR) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002051843-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | disclosed |