SCHEMBL7156993

SCHEMBL7156993

FC(F)(F)COC(Cl)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
HTT P42858 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11841959 0.77 MEN1 (0.46) MEN1KMT2AALDH1A1HSD17B10
SCHEMBL7158267 0.77
SCHEMBL11429308 0.74
SCHEMBL10429609 0.74
SCHEMBL7162550 0.74
SCHEMBL10159582 0.72
SCHEMBL11836936 0.72 MEN1 (0.71) MEN1KMT2AALDH1A1HSD17B10
SCHEMBL20746309 0.72 HTT (0.39) HTT
SCHEMBL596239 0.71 HTT (0.35) HTT
SCHEMBL8735140 0.70 MEN1 (0.46) MEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6551468-B1 No pressure is produced because hydrogen chloride dissolves in the aqueous layer O'DONNELL WILLIAM J (US) 2003-04-22 US disclosed
EP-1023254-A4 PREPARATION OF ISOFLURANE BY REACTION OF 2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER AND CHLORINE IN ADDED WATER, AT LOW TEMPERATURES AND/OR AT HIGHER CONVERSIONS HALOCARBON PROD CORP (US) 2002-11-04 EP disclosed
EP-1023254-A1 PREPARATION OF ISOFLURANE BY REACTION OF 2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER AND CHLORINE IN ADDED WATER, AT LOW TEMPERATURES AND/OR AT HIGHER CONVERSIONS Halocarbon Products Corporation (US) 2000-08-02 EP disclosed
WO-1999020588-A1 PREPARATION OF ISOFLURANE BY REACTION OF 2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER AND CHLORINE IN ADDED WATER, AT LOW TEMPERATURES AND/OR AT HIGHER CONVERSIONS HALOCARBON PRODUCTS CORPORATION (US) 1999-04-29 WO disclosed