SCHEMBL8735140

SCHEMBL8735140

FC(F)COC(Cl)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11841959 0.75 MEN1 (0.46) MEN1KMT2AALDH1A1HSD17B10
SCHEMBL11429308 0.72
SCHEMBL10429609 0.72
SCHEMBL9551131 0.72
SCHEMBL7156993 0.70 MEN1 (0.48) MEN1KMT2AALDH1A1HSD17B10
SCHEMBL15827471 0.68
SCHEMBL12924100 0.68
SCHEMBL15241367 0.68
SCHEMBL4082432 0.68
SCHEMBL4082435 0.68 CETP (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5419759-A Apparatus and methods for treatment of HIV infections and AIDS NAFICY SADEQUE S (US) 1995-05-30 US claimed
WO-2013106608-A1 PHARMACEUTICAL PRODUCT WITH CLOSURE ASSEMBLY BAXTER INTERNATIONAL INC. (US) 2013-07-18 WO disclosed
US-20130175235-A1 PHARMACEUTICAL PRODUCT WITH CLOSURE ASSEMBLY BAXTER HEALTHCARE S.A. (CH) 2013-07-11 US disclosed
EP-0659729-B1 Process for preparing chlorides of polyfluorochloro- and perfluoro carboxylic acids in the presence of chlorine SOLVAY FLUOR & DERIVATE (DE) 1998-06-24 EP disclosed
US-5569782-A Process for preparing polyfluorochlorocarbonyl chlorides and perfluorocarbonyl chlorides with addition of chlorine SOLVAY FLUOR UND DERIVATE GMBH (DE) 1996-10-29 US disclosed
EP-0659729-A1 Process for preparing chlorides of polyfluorochloro- and perfluoro carboxylic acids in the presence of chlorine Solvay Fluor und Derivate GmbH (DE) 1995-06-28 EP disclosed
EP-0525581-A3 COMPOSITIONS BASED ON 1-CHLORO-2,2,2-TRIFLUOROETHYL-DIFLUOROETHYLETHER FOR REMOVING WATER FROM SURFACES SOLVAY FLUOR & DERIVATE (US) 1993-10-20 EP disclosed
EP-0525581-A2 Compositions based on 1-chloro-2,2,2-trifluoroethyl-difluoroethylether for removing water from surfaces Solvay Fluor und Derivate GmbH (DE) 1993-02-03 EP disclosed