SCHEMBL71570

SCHEMBL71570

Nc1[nH]cnc1C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3258892 0.84 GDA (0.43)
SCHEMBL8024 0.82
SCHEMBL25275928 0.80 GDA (0.50)
Hydrochloric Acid SCHEMBL1775253 0.80 GDA (0.50)
SCHEMBL19018643 0.80 GAA (0.51)
SCHEMBL13176680 0.80
SCHEMBL12756128 0.78 HSD17B10 (0.48)
SCHEMBL11451266 0.77 CYP2C19 (0.39)
SCHEMBL5433655 0.77 NPSR1 (0.46)
SCHEMBL9576486 0.77 SMN1; SMN2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001602-B2 Diarylsulfide backbone containing photolabile protecting groups ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2021-05-11 US claimed
CN-110280220-A The preparation method of the carboxyl acid modified magnetic certain herbaceous plants with big flowers stem marrow adsorbent of 5- amino -1H- imidazoles -4- 济南大学 2019-09-27 CN claimed
US-20190112328-A1 DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS NIMBLEGEN SYSTEMS GMBH (DE) 2019-04-18 US claimed
US-10150791-B2 Diarylsulfide backbone containing photolabile protecting groups ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2018-12-11 US claimed
US-20170145047-A1 DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS NIMBLEGEN SYSTEMS GMBH (DE) 2017-05-25 US claimed
US-20160060286-A1 DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS NIMBLEGEN SYSTEMS GMBH (DE) 2016-03-03 US claimed
EP-2694525-B1 DIARYLSULPHID BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS ROCHE DIAGNOSTICS GMBH (DE) 2015-07-08 EP claimed
CN-103649102-A Diarylsulphid backbone containing photolabile protecting groups HOFFMANN LA ROCHE 2014-03-19 CN claimed
US-20140051605-A1 DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS NIMBLEGEN SYSTEMS GMBH (DE) 2014-02-20 US claimed
EP-2694525-A1 DIARYLSULPHID BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS Roche Diagnostics GmbH (DE) 2014-02-12 EP claimed
EP-1212338-B1 Nucleoside derivatives with photolabile protective groups DEUTSCHES KREBSFORSCH (DE) 2012-11-21 EP claimed
US-20120258891-A1 DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS NIMBLEGEN SYSTEMS GMBH (DE) 2012-10-11 US claimed
WO-2012136604-A1 DIARYLSULPHID BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS NIMBLEGEN SYSTEMS GMBH (DE) 2012-10-11 WO claimed
US-7432368-B2 Nucleosides with nitro-substituted anthraquin(thi)one, acridin(thi)one, xanthone or xanthione, or thioxanthone or thioxanthione, e.g., 5'-[2-nitro-9-oxo-3-(2-propyloxacarbonyl)thioxanthone]thymidine; used for synthesizing oligonucleotides or nucleic acid chips using light with wavelength above 390 mm ROCHE NIMBLEGEN, INC. (US) 2008-10-07 US claimed
EP-1589024-B1 Photolabile protecting groups NIMBLEGEN SYSTEMS INC (US) 2007-06-20 EP claimed
US-20050272076-A1 Photolabile protecting groups STENGELE, NIKOLAUS-PETER (DE) 2005-12-08 US claimed
EP-1589024-A1 Photolabile protecting groups Nimblegen Systems, Inc. (US) 2005-10-26 EP claimed
US-6756492-B1 Nucleoside derivatives with photo-unstable protective groups DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUND DES OFFENTLICHEN RECHTS (DE) 2004-06-29 US claimed
CN-117740961-A Compound analysis method of liquorice and liquorice probiotics fermentation preparation 北京中医药大学 2024-03-22 CN disclosed
CN-1332162-A Technological process of producing orotic acid SHANGHAI INST ORGANIC CHEM (CN) 2002-01-23 CN disclosed