Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576486 | 0.83 | SMN1; SMN2 (0.46) | GAAL3MBTL1TDP1ALDH1A1MEN1 | |
| SCHEMBL3258892 | 0.82 | GDA (0.43) | GAAL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL1560676 | 0.82 | GDA (0.41) | GAAL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL28488524 | 0.81 | GAA (0.68) | GAAL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL71570 | 0.80 | — | — | |
| SCHEMBL8024 | 0.80 | — | — | |
| SCHEMBL7435778 | 0.80 | GABRG2 (0.42) | GAAL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL7104572 | 0.79 | GAA (0.54) | GAAL3MBTL1TDP1ALDH1A1P2RX7 | |
| SCHEMBL11451266 | 0.79 | CYP2C19 (0.39) | GAAL3MBTL1TDP1ALDH1A1P2RX7 | |
| SCHEMBL6314836 | 0.79 | GAA (0.36) | GAAL3MBTL1TDP1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100849-A1 | 6-OXOPURINE PHOSPHORIBOSYL TRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-06-22 | — | — | WO | disclosed |