Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 16/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157275 | 1.00 | MAOA (0.53) | MAOAMAOBF10ITGB3PRSS1 | |
| SCHEMBL7161503 | 0.91 | MAOA (0.55) | MAOAMAOBF10ITGB3PRSS1 | |
| SCHEMBL7161497 | 0.91 | MAOA (0.55) | MAOAMAOBF10ITGB3PRSS1 | |
| SCHEMBL7160208 | 0.89 | MAOB (0.71) | MAOAMAOBF10 | |
| SCHEMBL7160205 | 0.89 | MAOB (0.71) | MAOAMAOBF10 | |
| SCHEMBL7154323 | 0.88 | MAOA (0.54) | MAOAMAOBF10F2 | |
| SCHEMBL7154325 | 0.88 | MAOA (0.54) | MAOAMAOBF10F2 | |
| SCHEMBL6040345 | 0.87 | MAOA (0.60) | MAOAMAOBF10ITGB3PRSS1 | |
| SCHEMBL6040338 | 0.87 | MAOA (0.60) | MAOAMAOBF10ITGB3PRSS1 | |
| SCHEMBL7157295 | 0.87 | MAOA (0.59) | MAOAMAOBF10ITGB3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6537986-B2 | With thiourea, thioamide, or dithiocarbamate functionality; (S)-N-(((3-(3-fluoro-4-morpholinyl)phenyl)-2-oxo-5 -oxazolidinyl)methyl)thioacetamide for example; treats multiple-resistant staphylococci | PHARMACIA & UPJOHN COMPANY | 2003-03-25 | — | — | US | claimed |