Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.69 |
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872645 | 0.81 | PGR (1.00) | PGRARNR3C1NR3C2 | |
| SCHEMBL17552287 | 0.75 | PGR (0.56) | PGRARNR3C1NR3C2 | |
| SCHEMBL4171050 | 0.74 | PGR (0.69) | PGRARNR3C1NR3C2 | |
| SCHEMBL3381738 | 0.74 | PGR (0.55) | PGRARNR3C1NR3C2 | |
| SCHEMBL14553143 | 0.74 | PGR (0.72) | PGRARNR3C1NR3C2 | |
| SCHEMBL3883683 | 0.74 | PGR (0.86) | PGRARNR3C1NR3C2 | |
| SCHEMBL7541099 | 0.73 | PGR (0.81) | PGRARNR3C1NR3C2 | |
| SCHEMBL5111383 | 0.72 | PGR (0.69) | PGRARNR3C1NR3C2 | |
| SCHEMBL10956623 | 0.71 | PGR (0.56) | PGRARNR3C1NR3C2 | |
| SCHEMBL12460695 | 0.71 | PGR (0.77) | PGRARNR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509334-B1 | This invention relates to compounds that antagonists of the progesterone receptor, their preparation and utility. Intracellular receptors (IR) form a class of structurally related gene regulators known as \"ligand dependent | AMERICAN HOME PRODUCTS CORPORATION | 2003-01-21 | — | — | US | disclosed |