SCHEMBL715786

SCHEMBL715786

N=C=NCC(Cl)CCCCCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8940735 0.79
SCHEMBL29105368 0.69 TSHR (0.40)
SCHEMBL3696440 0.67 ALDH1A1 (0.32)
SCHEMBL16669025 0.67 ALDH1A1 (0.32)
SCHEMBL11696701 0.66
SCHEMBL1446445 0.66 ALDH1A1 (0.35)
SCHEMBL9734937 0.64 TSHR (0.36)
SCHEMBL9788423 0.64
SCHEMBL497040 0.62
SCHEMBL4443603 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915449-B1 SIRNA-HYDROPHILIC POLYMER CONJUGATES FOR INTRACELLULAR DELIVERY OF SIRNA AND METHOD THEREOF BIONEER CORP (KR) 2016-03-23 EP claimed
US-8969543-B2 SiRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof BIONEER CORPORATION (KR) 2015-03-03 US claimed
US-20130064786-A1 siRNA HYDROGEL AND METHOD FOR MANUFACTURING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY 2013-03-14 US claimed
JP-2009504179-A 2009-02-05 JP claimed
EP-1915449-A1 SIRNA-HYDROPHILIC POLYMER CONJUGATES FOR INTRACELLULAR DELIVERY OF SIRNA AND METHOD THEREOF Bioneer Corporation (KR) 2008-04-30 EP claimed
US-20070287681-A1 siRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof BIONEER CORPORATION (KR) 2007-12-13 US claimed
US-20070270484-A1 3'-N-Substituted-3-O-Substituted Erythronolide a Derivatives RANBAXY LABORATORIES LIMITED (IN) 2007-11-22 US claimed
US-20070066837-A1 Podophyllotoxin derivatives as antitumor agents RANBAXY LABORATORIES LIMITED (IN) 2007-03-22 US claimed
WO-2007021142-A1 SIRNA-HYDROPHILIC POLYMER CONJUGATES FOR INTRACELLULAR DELIVERY OF SIRNA AND METHOD THEREOF BIONEER CORPORATION (KR) 2007-02-22 WO claimed
EP-1599485-A2 PODOPHYLLOTOXIN DERIVATIVES AS ANTITUMOR AGENTS RANBAXY LABORATORIES, LTD. (IN) 2005-11-30 EP claimed
WO-2005030786-A1 3'-N-SUBSTITUTED-3-O-SUBSTITUTED ERYTHRONOLIDE A DERIVATIVES RANBAXY LABORATORIES LIMITED (US) 2005-04-07 WO claimed
WO-2004073375-A2 PODOPHYLLOTOXIN DERIVATIVES AS ANTITUMOR AGENTS RANBAXY LABORATORIES LIMITED (IN) 2004-09-02 WO claimed
JP-2174787-A None JP disclosed
JP-55164687-A None JP disclosed
JP-4112890-A None JP disclosed
JP-8268970-A None JP disclosed
JP-S55164687-A NOVEL MAYTANSINOID COMPOUND AND ITS PREPARATION TAKEDA CHEM IND LTD 1980-12-22 JP disclosed
US-4232111-A COMPRISING A COPOLYMER OF METHACRYLIC OR ACRYLIC ACID AND STYRENE OR A VINYL TOLUENE FUJI PHOTO FILM CO., LTD. (JP) 1980-11-04 US disclosed
US-4161532-A PSYCHOLOGICAL DISORDERS, PSYCHOTROPIC SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) 1979-07-17 US disclosed
EP-0001841-A2 Tylosin derivatives SANRAKU-OCEAN CO., LTD. (JP) 1979-05-16 EP disclosed